Christina C. Lawson, PhD, Candice Y. Johnson, PhD, Feiby L. Nassan, ScD, MBBCH, Thomas H. Connor, PhD, James M. Boiano, MS, Carissa M. Rocheleau, PhD, Jorge E. Chavarro, MD, ScD, and Janet W. Rich-Edwards, ScD.
Purpose: The purpose of this study was to quantify the urine concentration of non-metabolized cyclophosphamide (CP), a commonly administered antineoplastic drug, among potentially exposed Canadian healthcare workers and to identify factors associated with the drug concentration levels.
S. Ndaw, F. Denis, P. Marsan, A. Rémy, A. Robert, Département Toxicologie et biométrologie, INRS.
Utilisés dans le traitement des cancers, les médicaments cytotoxiques présentent une toxicité intrinsèque, du fait de leurs propriétés génotoxiques, cancérogènes et tératogènes. Une étude réalisée dans 12 établissements hospitaliers, pour évaluer les expositions à ces substances, a montré que plus de la moitié des professionnels suivis avait des niveaux quantifiables de cytotoxiques dans leurs urines.
Mari A. Bernabeu-MartõÂnez, Mateo Ramos Merino, Juan M. Santos Gago, Luis M.AÂ lvarez Sabucedo, Carmina Wanden-Berghe, Javier Sanz-Valero.
– Objective: To review the scientific literature related to the safe handling of hazardous drugs (HDs).
– Method: Critical analysis of works retrieved from MEDLINE, the Cochrane Library, Scopus, CINHAL, Web of Science and LILACS using the terms “Hazardous Substances”, “Antineoplastic Agents” and “Cytostatic Agents”, applying “Humans” and “Guidelines” as filters. Date of search: January 2017.
Sophie Ndaw, Alain Robert, Claire Ricolfi, Flavien Denis, Philippe Marsan
Les médicaments cytotoxiques utilisés dans les traitements des cancers présentent une toxicité intrinsèque, du fait de leurs propriétés génotoxiques, tératogènes et cancérigènes.
Maximilien Lefebvre, Nicolas Simon, Michèle Vasseur, Ousseini Sidikou, Christine Barthélémy, Bertrand Décaudin and Pascal Odou.
Purpose: The aims of this study were to propose a simple methodology to assess the rinsing volume of syringe extension sets and to compare several marketed devices.
Seth Eisenberg Abstract: The risks associated with hazardous drug (HD) handling have been well documented in the literature, dating back more than 35 years (Centers for Disease Control and Prevention, 2004; Crudi, Stephens, & Maier, 1982; Lorente et al.,...
Amy Callahan, DNP, RN, CRNP, AOCNS®, Nancy J. Ames, RN, PhD, Mary Lou Manning, PhD, CRNP, CIC, FAAN, Kate Touchton-Leonard, MA, Li Yang, MS, and Gwenyth R. Wallen, RN, PhD.
Purpose/Objectives—To identify factors associated with oncology nurses’ use of hazardous drug (HD) safe-handling precautions in inpatient clinical research units.
Pablo Martín Lancharro, Nuria de Castro-Acuña Iglesias, Francisco-Javier González-Barcala, José Domingo Moure González
Objective: Provide updated evidence and learn about the actions that must be implemented in order to prevent the occupational exposure to cytostatic drugs
Chun-Yip Hon, Kay Teschke, Hui Shen, Paul A. Demers, Scott Venners
Purpose: The purpose of this study was to quantify the urine concentration of non-metabolized cyclophosphamide (CP), a commonly administered antineoplastic drug, among potentially exposed Canadian healthcare workers and to identify factors associated with the drug concentration levels.
Seth Eisenberg
The dangers associated with handling hazardous drugs (HDs) have been well documented. Contamination of the healthcare environment, which can occur during compounding and administration, may lead to drug absorption by healthcare workers.